Laxogenin | Reviews, Dosage, and Clinical Trials

Dr. Mike Jansen

Last Updated December 17, 2022

Dr. Mike Jansen

 December 17, 2022

Curious about laxogenin reviews, dosage, and clinical trials?

Do you wonder what real-world users and the latest research studies have to say about the effectiveness of laxogenin?

Then you’ve come to the right place. In this comprehensive guide, we detail everything you need to know about laxogenin reviews, dosage, and clinical trials, including the feedback from thousands of verified customers.

We also answer your most important laxogenin questions, including:

  • Does laxogenin actually work?
  • Does laxogenin impact your testosterone levels?
  • Do I have to cycle laxogenin?

…And so much more!

Our team at testosterone.org has analyzed data from all the latest laxogenin studies, as well as recent customer reviews to give you science-based information on laxogenin.

Of course, at the end of the day it’s up to you to decide whether or not you should add laxogenin to your supplement regimen.

Now let’s get started!

Disclaimer: The contents of Testosterone.org are for informational and educational purposes. We do not provide legal advice. Likewise, we do not provide medical advice, diagnosis, or treatment. Please consult your physician prior to consuming any over-the-counter supplements, like a natural testosterone booster, and/or getting a prescription for a pharmaceutical medication. Your access to Testosterone.org is subject to our full disclaimer and terms of use.


What is Laxogenin?

Laxogenin is one of the most popular “legal steroid alternatives” on the market today. But what is it, and why do some people think it works for boosting muscle mass?

Laxogenin belongs to a family of natural plant steroids called “brassinosteroids.”

These compounds increase protein synthesis in plants, and play a key role in their overall growth and development.

Many plant steroids, such as ecdysterone, have been shown to boost protein synthesis in animal and human studies (1, 2). Therefore, some people believe that brassinosteroids such as laxogenin may have similar muscle-building effects.

Laxogenin is commonly derived from the plant smilax sieboldii.

However, other plants such as the Chinese onion allium chinense also contain significant amounts of laxogenin.

Structurally, laxogenin is very similar to the molecule testosterone. However, unlike testosterone, laxogenin does not bind to the androgen receptors in humans.

Instead, it is theorized to work by directly increasing muscle protein synthesis inside the muscle cells, without impacting your hormone levels. This is good news for anyone who is interested in building muscle mass and strength as a “natural athlete.”

The research on laxogenin is still in its infancy.

Only a small number of animal studies have been performed studying the potential muscle-building effects of laxogenin supplementation.

To date, no human studies have been performed on the compound, although that may change in the future, based on the positive results many people are seeing with this natural plant steroid.


Laxogenin Reviews


Laxogenin Benefits

Many first-time users are reporting faster overall progress while using laxogenin. This makes perfect sense, as other natural plant steroids have also been shown to produce results in human subjects.

But what benefits are users actually reporting while using laxogenin?

Based on extensive research, here are the most commonly reported benefits while using laxogenin (3, 4):

  • Faster size and strength gains
  • Improved recovery ability
  • Enhanced muscular endurance

Let’s take an closer look at each of these benefits.

Many users report faster size and strength gains after just 1-2 weeks using laxogenin.

This sounds too good to be true, but these are verified customers with no affiliation with any supplement company.
Based on our research, we think the accelerated size and strength gains may be caused by elevated protein synthesis levels. Research shows that other natural plant steroids can increase protein synthesis levels in humans, so its very possible the same thing is happening with laxogenin (5, 6).

Another reported benefit from taking laxogenin is improved recovery ability.

Many users are reporting less overall muscle soreness following intense exercise. Other users say they have been able to train more often during the week and still recover.

This is obviously good news if you are trying to get bigger and stronger.

Finally, some users say their muscular endurance has improved. They can perform more sets during a workout, and they can get more reps with the same weight.

Of course, human studies are needed to confirm these results. But so far, the benefits seen in real-world users are very promising.


Laxogenin Side Effects

Based on our research, most users do not experience any side effects while taking laxogenin. However, there are a few potential side effects that you should be aware of.

Here are some of the most common side effects reported while cycling laxogenin:

  • Nausea or upset stomach
  • Minor headaches
  • Heavy Urination
  • Diarrhea

Let’s take a closer look at each of these side effects.

The most common symptom that most people experience while taking laxogenin is nausea and / or an upset stomach.

This makes sense, as almost any supplement has the potential to cause these symptoms – especially if they are taken on an empty stomach.

If you are experiencing one of these symptoms, then an easy solution would be to lower your dose, or to take laxogenin with a whole food meal.

Other users reported symptoms like minor headaches and heavy urination.

We were not able to find any user reports of diarrhea, but other laxogenin resources listed it as a possible symptom, so we included it here to be complete.

Of course, we will have to wait for more animal and human studies on laxogenin to better understand its potential side effects.


Laxogenin Reviews


Is Laxogenin Safe?

Laxogenin is quickly becoming one of the most popular “legal steroid alternatives” in the world today. But is it really safe?

Based on our research, we believe that laxogenin is perfectly safe for human consumption. Here are the main factors supporting our conclusion:

  • Few user-reported side effects
  • Does not impact hormones
  • Does not require a PCT
  • Natural plant steroid

Let’s take a closer look at each of these factors.

Laxogenin is one of the few supplements with almost no reported side effects.

Thousands of people have used Laxogenin, and based on our research, it’s rare that someone reports more than an upset stomach or a minor headache while using it.

Laxogenin also does not impact your hormone levels, which means it does not require a PCT, or post-cycle therapy.

Finally, laxogenin is considered a “natural plant steroid.” Other natural plant steroids including ecdysterone and turkesterone are extremely safe, so it’s reasonable to conclude that laxogenin would be as well.

Overall, laxogenin appears to be a very safe supplement to take. Of course, further research is required in this area.


Laxogenin Review | The A-Z Guide

Many fitness experts believe that laxogenin is the hottest new “legal steroid alternative” in the world today. But what is it, and why does it work so well for building muscle mass and strength?

Laxogenin belongs to a family of natural plant steroids called “brassinosteroids.”

Plants produce laxogenin because it boosts protein synthesis, and dramatically speeds up their overall growth and development.

Indeed, several research studies show that brassinosteroids have a powerful anabolic effect on plant cells (3, 4).

Fortunately, there is some evidence that laxogenin and other brassinosteroids boost muscle growth in human muscle cells. For example, some studies show that brassinosteroids activate AKT1 proteins inside muscle cells, which increases protein synthesis (7, 8).

Other studies show that laxogenin has the potential to block enzymes that break down cAMP, which also increases muscle growth (9).

Brassinosteroids like laxogenin even have the potential to reduce tissue damage caused by free radicals, which could mean faster recovery from your most intense workouts (10, 11).

Here is a quick summary of the potential benefits of laxogenin, based on these research studies:

  • Increased protein synthesis
  • Elevated AKT1 proteins
  • Elevated cAMP
  • Reduced free radical damage

The short answer is laxogenin has the potential to dramatically improve your size and strength gains, while improving your workout performance and speeding up your recovery ability.

Talk about a powerful supplement!

Based on this research, many bodybuilders and fitness enthusiasts have begun supplementing their diet with laxogenin.

This makes sense, as laxogenin is primarily found in Chinese onions and other rare vegetables, so getting enough laxogenin through diet alone may be impractical.

So what kinds of results are people seeing?

Many verified customers claim that they are building as much as 5-10 pounds of lean muscle mass during their first 6-12 week cycle. This is very impressive, as it normally takes a natural bodybuilder up to a year to gain that much muscle mass!

So far, very few human studies have been performed on laxogenin.

Because of this, it’s hard to say for sure how effective laxogenin is. However, there are plenty of studies on other natural plant steroids, like ecdysterone and turkesterone.

And so far, the results are very promising.
Research shows that other natural plant steroids like ecdysterone and turkesterone can increase muscle protein synthesis by as much as 20%!

Many fitness experts believe that laxogenin should have similar results, which would be extremely impressive.

Here are some of the main benefits of laxogenin, as reported by verified customers:

  • Increased muscle mass
  • Increased strength
  • Reduced body fat
  • Faster recovery from workouts
  • Improved muscular endurance

As you can see, laxogenin has a wide range of benefits. It is a perfect choice for anyone who is interested in making faster gains in the gym.

Of course, laxogenin is still a new product, and more research is required to figure out exactly how effective it is.

However, the anecdotal evidence from real-world customers is extremely promising.


Laxogenin Reviews


Best Laxogenin Supplements

Without further ado, here is the Testosterone.org list of the best laxogenin supplements available in 2023.

1. Huge Supplements Sapogenix

Here at Testosterone.org, we believe that Huge Supplements Sapogenix is the #1 laxogenin product on the market today.

Sapogenix is more than just a laxogenin product: it also contains a number of other anabolic growth factors, including laxogenin, 6-keto-disogenin, spirostanol sapogenins, furastanolic sapogenins, and many others.

Sapogenix uses a proprietary blend of anabolic ingredients so you can get the absolute best results possible.

Based on the dozens of positive customer reviews, it looks like Sapogenix is the real deal.

We also like Huge Supplements because of their fast and reliable shipping, as well as their superior customer service.

Finally, Huge Supplements manufactures all of their products right here in the United States under FDA regulated facilities. This means they only use the purest ingredients in their products.

Servings: 60

Amount per serving: 250

Order Laxogenin from our top-rated USA vendor...


2. Huge Supplements Annihilate

Huge Supplements sells another laxogenin supplement called Annihilate. This product contains 100 mg of laxogenin per serving and nothing else!

As an added bonus, Huge Supplements uses a patented cyclosome delivery technology to ensure superior absorption of their product.

This makes Annihilate a great choice for anyone who wants to get bigger and stronger with laxogenin, but isn’t ready to try the flagship product Sapogenix.

Servings: 60

Amount per serving: 100

Order the best Laxogenin from Huge Supplements...


3. Redcon1 Halo

Redcon1 is one of the most trusted and reliable supplement companies in the United States.

They manufacture a laxogenin product called Halo using high-quality Chinese Smilax, aka one of the most potent sources of laxogenin in the world.

Servings: 60

Amount per serving: 100

Click here if you want to learn more about Redcon1 Halo.


 4. Hi-Tech Laxogenin 100

Hi-Tech Pharmaceuticals produces a high-quality laxogenin product called Laxogenin 100.

Unlike other laxogenin manufacturers, Hi-Tech includes cyclosome technology in all of their products to ensure superior absorption.

Servings: 60

Amount per serving: 100

Order the best Laxogenin from a USA vendor...


Laxogenin Dosage

By now you’re probably wondering about how much laxogenin you should take per day for optimal results.

You want a dose that is high enough to get fast results, but low enough that you do not experience any negative side effects.

Based on our research, the optimal dose for laxogenin is 100 – 200 mg per day for 6-12 weeks at a time.

Most users report noticeable size and strength gains at this dose, with minimal side effects.

We recommend that you start out at a dose of 100 mg per day so that you can assess its effects. If you are not experiencing any side effects, then you and bump the dose up to 200 mg per day and see how you respond.

Most users report faster progress at a dose of 200 mg per day.

This is usually split up into two equal doses of 100 mg, such as in the morning and the evening. We recommend that you take no more than 200 mg of laxogenin per day, as some users report minor side effects at this point.

Of course, further research is required to pinpoint the optimal laxogenin dosage.

However, based on anecdotal evidence, we recommend a dose of 100 – 200 mg per day for 6-12 weeks at a time. This dose should give you maximum results, while minimizing any negative side effects.


Laxogenin Reviews


Laxogenin Cycle

Laxogenin is one of the most powerful “legal steroid alternatives” on the market today.

Laxogenin does NOT impact your hormone levels, which means you could use the product year-round. However, most users choose to “cycle” laxogenin for 1-3 months at a time before taking a break from the product.

Here at testosterone.org, we think this is a very smart decision, as we don’t have any studies on the long-term safety of laxogenin.

So what’s the optimal way to cycle laxogenin? Based on our research, the optimal laxogenin cycle is 100 – 200 mg per day for 6-12 weeks at a time.

After your 6-12 week cycle, you should take a 4-8 week break from laxogenin before performing your next cycle.

Based on feedback from dozens of verified customers, a 6-12 week cycle should maximize your results while minimizing the risk of negative side effects.


Is Laxogenin a Steroid?

You might be wondering if laxogenin is classified as an anabolic steroid. Fortunately, the answer is a simple “no.”

Laxogenin is considered a natural plant steroid, but this is completely different from traditional anabolic steroids. Laxogenin does NOT impact your total testosterone levels or other hormones.

This means you don’t have to worry about any of the long-term side effects of traditional steroids.

Some users choose to “cycle” laxogenin for 6-12 weeks at a time. However, this is not strictly necessary, as there is no need to perform a post-cycle therapy while using this product.

This makes laxogenin a great choice for the drug-free athlete who wants to get an extra edge over their competition.


Laxogenin Reviews


Does Laxogenin Suppress Testosterone?

Most people choose to cycle laxogenin for 6-12 weeks at a time.

Some people believe this is because laxogenin suppresses your natural testosterone production. But is that really true?

Based on our research, laxogenin does NOT suppress your natural testosterone production. Instead, it probably works by increasing protein synthesis levels inside your muscle cells.

This makes laxogenin a great choice for the natural athlete who doesn’t want to use anything that might impact their hormone levels.

Of course, more research is required on how laxogenin impacts your hormone levels. However, other “natural plant steroids” like ecdysterone and turkesterone do not suppress testosterone levels in humans, so it makes sense that laxogenin would also have little impact.


Does Laxogenin Work?

Laxogenin is one of the most popular over-the-counter products in the world today. But does it work as well as people claim it does?

The truth is, there are no long-term research studies on laxogenin. However, based on reviews from thousands of verified customers, laxogenin appears to be an extremely effective product for building muscle mass and strength.

Users are reporting extremely fast gains – the kind you would expect from a mild steroid cycle!

The most common benefits that people are seeing from laxogenin include increased size and strength gains, as well as faster recovery ability and reduced body fat levels.

More research is required to find out exactly how effective laxogenin is. However, the anecdotal evidence for laxogenin shows that it works extremely well for most people.


Laxogenin Reviews


Laxogenin | Reviews, Dosage, and Clinical Trials

In conclusion…

Laxogenin is one of the most promising new supplements in the fitness industry today.

So far, few research studies have been performed on this “legal steroid alternative.” However, the user reviews from verified customers are absolutely incredible, which shows that laxogenin consistently produces real-world results.

Because laxogenin is so new, there is a lot of confusion around the product.

Based on our research, laxogenin appears to be extremely effective for building muscle mass and strength, as well as promoting fat loss.

The optimal laxogenin dose is roughly 100-200 mg per day for 6-12 weeks, followed by a 4-8 week break from the product.

And while there are no clinical trials on laxogenin, it appears to be a perfectly safe supplement with no long-term side effects – especially if you follow our recommended dosing protocol.

So what are you waiting for?

Get your hands on some Huge Supplements laxogenin today and take your physique to the next level!


References

  1.  Isenmann E, Ambrosio G, Joseph JF, Mazzarino M, de la Torre X, Zimmer P, Kazlauskas R, Goebel C, Botrè F, Diel P, Parr MK. Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans. Arch Toxicol. 2019 Jul;93(7):1807-1816. doi: 10.1007/s00204-019-02490-x. Epub 2019 May 23. PMID: 31123801.
  2.  Parr MK, Botrè F, Naß A, Hengevoss J, Diel P, Wolber G. Ecdysteroids: A novel class of anabolic agents?. Biol Sport. 2015;32(2):169-173. doi:10.5604/20831862.1144420
  3.  Bishop GJ, Koncz C. Brassinosteroids and plant steroid hormone signaling. Plant Cell. 2002;14 Suppl(Suppl):S97-S110. doi:10.1105/tpc.001461
  4.  Wang Q, Xu J, Liu X, Gong W, Zhang C. Synthesis of brassinosteroids analogues from laxogenin and their plant growth promotion. Nat Prod Res. 2015;29(2):149-57. doi: 10.1080/14786419.2014.968151. Epub 2014 Oct 14. PMID: 25311045
  5.  Syrov VN, Kurmukov AG. Ob anabolicheskikh svostvakh fitoekdizona turkesterona i tetraatsetata turkesterona v opytakh na samtsakh krys [The anabolic properties of turkesterone phytoecdysone and turkesterone tetraacetate in experiments on male rats]. Probl Endokrinol (Mosk). 1976 May-Jun;22(3):107-12. Russian. PMID: 935080.
  6.  Dinan L, Bourne P, Whiting P, Tsitsekli A, Saatov Z, Dhadialla TS, Hormann RE, Lafont R, Coll J. Synthesis and biological activities of turkesterone 11alpha-acyl derivatives. J Insect Sci. 2003;3:6. doi: 10.1093/jis/3.1.6. Epub 2003 Feb 24. PMID: 15841223; PMCID: PMC524646.
  7.  Hajduch E, Alessi DR, Hemmings BA, Hundal HS. Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells. Diabetes. 1998 Jul;47(7):1006-13. doi: 10.2337/diabetes.47.7.1006. PMID: 9648821.
  8.  Rommel C, Bodine SC, Clarke BA, Rossman R, Nunez L, Stitt TN, Yancopoulos GD, Glass DJ. Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways. Nat Cell Biol. 2001 Nov;3(11):1009-13. doi: 10.1038/ncb1101-1009. PMID: 11715022.
  9.  Hursel R, Westerterp-Plantenga MS. Thermogenic ingredients and body weight regulation. Int J Obes (Lond). 2010 Apr;34(4):659-69. doi: 10.1038/ijo.2009.299. Epub 2010 Feb 9. PMID: 20142827.
  10.  Zhang YW, Morita I, Zhang L, Shao G, Yao XS, Murota S. Screening of anti-hypoxia/reoxygenation agents by an in vitro method. Part 2: Inhibition of tyrosine kinase activation prevented hypoxia/reoxygenation-induced injury in endothelial gap junctional intercellular communication. Planta Med. 2000 Mar;66(2):119-23. doi: 10.1055/s-2000-11126. PMID: 10763583.
  11.  Zhang YW, Morita I, Shao G, Yao XS, Murota S. Screening of anti-hypoxia/reoxygenation agents by an in vitro model. Part 1: Natural inhibitors for protein tyrosine kinase activated by hypoxia/reoxygenation in cultured human umbilical vein endothelial cells. Planta Med. 2000 Mar;66(2):114-8. doi: 10.1055/s-2000-11128. PMID: 10763582.
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